File Name: behavioral signs of schizoidia and schizotypy in social anhedonics.zip
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Schizotypal personality features and certain neurocognitive deficits have been shown to aggregate in the relatives of schizophrenic patients, supporting the view that both are likely to reflect genetic contributions to liability to schizophrenia. Within the relatives of schizophrenic patients, however, the interrelationships between these potential indicators of liability to schizophrenia are not well known. Using data from the UCLA Family Study, we examine the interrelationships between personality disorder symptoms and neurocognitive functioning in nonpsychotic first-degree relatives of schizophrenic patients.
Cognition across the psychiatric disorder spectrum: From mental health to clinical diagnosis View all 12 Articles. Behavioral and cognitive dysfunction, particularly social and communication impairments, are shared between autism and schizophrenia spectrum disorders, while evidence for a diametric autism-positive schizophrenia symptom profile is inconsistent. We investigated the shared phenotype at a personality trait level, particularly its resemblance to schizoid personality disorder, as well as differential aspects of the autism—schizophrenia model. Items of the autism spectrum quotient AQ and schizotypal personality questionnaire SPQ were pseudo-randomly combined, and were completed by male, female non-clinical participants aged 18— A factor analysis revealed three factors; the first represented a shared social disorganization phenotype, the second reflected perceptual oddities specific to schizotypy while the third reflected social rigidity specific to autism.
Jack J. Blanchard, Lindsay M. Collins, Minu Aghevli, Winnie W. Leung, Alex S. Social anhedonia has been employed in psychometric high-risk studies to identify putative schizotypes.
Anhedonia is a diverse array of deficits in hedonic function, including reduced motivation or ability to experience pleasure. Re-conceptualizations of anhedonia highlight the independence of "wanting" and "liking". Anhedonia has also been used to refer to "affective blunting", "restricted range of affect", "emotional numbing", and "flat affect", particularly in the context of post-traumatic stress disorders. In PTSD patients, scales measuring these symptoms correlate strongly with scales that measure more traditional aspects of anhedonia, supporting this association. Studies in clinical populations, healthy populations, and animal models have implicated a number of neurobiological substrates in anhedonia. Regions implicated in anhedonia include the prefrontal cortex as a whole, particularly the orbitofrontal cortex OFC , the striatum , amygdala , anterior cingulate cortex ACC , hypothalamus , and ventral tegmental area VTA.
A community sample of 88 putative schizotypes 48 social anhedonics, 40 controls , aged 18 to 19 years, and their biological parents 42 mothers of social anhedonics, 37 mothers of controls; 24 fathers of social anhedonics, 20 fathers of controls receive videotaped diagnostic evaluations that serve as the basis for ratings of behavioral signs of schizoidia and schizotypy. Proband social anhedonics exhibit more atypical interpersonal behaviors characteristic of schizoid and schizotypal personality disorders than controls. Mothers of social anhedonics display more atypical interpersonal behaviors characteristic of schizotypal personality disorder than mothers of controls.
William P. Horan, Jack J.
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